| ACL Laboratories |
| Allina Hospitals and Clinics |
| Alverno Information Services |
| American Academy of Dermatology Association |
| Ascension Health |
| Banner Health |
| Baylor College of Medicine-Houston |
| Baylor Health Care System |
| Beth Israel Deaconess Medical Center |
| BJC Health System |
| * Blue Cross Blue Shield of Alabama |
| Blue Cross Shield of Massachusetts |
| Camcare, Inc. |
| Cancer Care Ontario |
| Cape Cod Healthcare |
| Caritas Christi Hospital System |
| Carolinas HealthCare System |
| Center for Medicare / Medicaid Services (CMS) |
| Child Health Care Corporation of America |
| Children's Healthcare of Atlanta |
| Children's Health System |
| Children's Hospital |
| CHRISTUS Health Southeast Texas |
| Cincinnati Children's Hospital Medical Center |
| Cleveland Clinic |
| Dartmouth-Hitchcock Medical Center |
| Denver Health and Hospitals |
| Duke University Health Systems |
| Emergency Mecial Associates (EMA) |
| Evanston Northwestern Healthcare |
| Fairview Health Services |
| First Health Services Corp. |
| Geisinger Health System |
| Grady Health System |
| Group Health Cooperative |
| Harris County Hospital District |
| Harvard Pilgrim HealthCare |
| Harvard Vanguard Medical Associates |
| HealthCare Partners Medical Group |
| Hospital Corporation of America |
| * Intermountain Health Care |
| JPS Health Network |
| King's Consulting |
| M. D. Anderson Cancer Center |
| Markcelian Analytics, Inc. |
| Marshfield Clinic |
| Matria Healthcare, Inc. |
| Mayo Clinic Jacksonville |
| Mayo Clinic Rochester |
| Mayo Clinic Scottsdale |
| Medica |
| MedStar Health |
| National Assocation of Children's Hospitals and Related Institutions (NACHRI) |
| National Jewish Medical and Research Center |
| New York Presbyterian Hospital |
| Northwestern Medical Faculty Foundation |
| Northwestern Memorial Hospital |
| Northwestern University Medical School |
| Olmsted Medical Center |
| Oregon Community Health Information Network (OCHIN, Inc.) |
| Oregon Health and Science University |
| OSF Healthcare System |
| Palo Alto Medical Foundation |
| Park Nicollet Health Services |
| Partners HealthCare |
| Peace Health |
| * Presbyterian Healthcare Services |
| ProHealth Care |
| Providence Health System |
| Quest Diagnostics |
| Rush University Medical Center |
| SMDC |
| SSM |
| St. Vincent's Medical Center |
| Salem Hospital |
| Scripps Health |
| Sharp Healthcare |
| Shriners Hospitals for Children |
| Sisters of Mercy Health System |
| Spectrum Health |
| Sutter Health |
| Tenet Healthcare |
| Texas Children's Hospital |
| The Children's Hospital, Denver |
| The Institute for Urban Family Health |
| The Ottawa Hospital |
| ThedaCare |
| Trinity Health |
| United HealthGroup |
| University of Michigan Health System |
| University of Minnesota Medical School |
| University of Ottawa |
| University of Pittsburgh Medical Center |
| University of Texas Southwestern Medical Center |
| University of Utah Health Science Center |
| University of Victoria – School of Health Information Science |
| University of Virginia Health System |
| US Oncology |
| Veterans Health Administration |
| |
| * Founding Member |
